New genetic mapping improves optimal treatment for intrahepatic cholangiocarcinoma

Molecular staging of intrahepatic cholangiocarcinoma (iCCA)

picture: To address this challenge, the team identified low-intratumor heterogeneity/high-intertumor variability (LIHV) genes. This signature of 1,341 genes targets markers that remain consistent within a human tumor but vary greatly between patients. By filtering out the discrepant “noise”, the LIHV design enables a robust and reproducible classification of iCCA into five molecular subtypes, each associated … Read more

South Africa’s MeerKAT telescope is mapping the previously unseen regions between galaxies – and has discovered 60 new cosmic structures.

South Africa's MeerKAT telescope is mapping the previously unseen regions between galaxies - and has discovered 60 new cosmic structures.

Astronomers are discovering things that were once hidden inside some of the largest objects in the universe, known as galaxies. Using the powerful MeerKAT radio telescope in South Africa, researchers have mapped the extinction, the scattering of radio emissions, a signal that reveals the energetic processes that occur in the large spaces between galaxies when … Read more